|Debut Appearance||Super Mario World|
|Latest Appearance||Super Mario Advance 2: Super Mario World|
 Super Mario Series
 Super Mario World
They would debut in Super Mario World. They can only be found in the cave levels with being first seen in Chocolate Island 4. They cannot be defeated by a stomp or a spin jump or the fireballs from Fire Mario or Fire Luigi. They can only be defeated by the Cape's spinning attack, a Star or using a Block or Shell. They are immune to hazards like Munchers and spikes so they are useful for getting across these hazards. They do not pop out of the ground and can be eaten and swallowed by Yoshi.
 Super Mario 3D Land
They will appear in Super Mario 3D Land for their first appearance in ten years. They will again inhabit caves. Mega Moles will no longer wear glasses and have a darker color than they did in Super Mario World.
 Nintendo Adventure Books
They would appear in the Nintendo Adventure Book Dinosaur Dilemma. If Mario offers an apple to Yoshi and other dinosaurs near Lake Trilobite will turn out to be Mega Moles in disguise and attack Mario after they remove the costumes, and lead to a Game Over. Mega Moles can also be found in a decrepit mansion, and Mario is able to escape them by stepping to the side. Attempting to outrun them, will lead to a Game Over as Mario would fall into a watery pit with a Blargg.
They would also appear in the crowds at the International Dino-Flying Derby in Flown the Koopa, and would eye Mario hungrily while the show ends. If Mario and Luigi put on Mega Mole costumes, real ones will approach them with gifts and take them to their cave if the Mario Bros. agree to follow. Once in the cave, the Mega Moles will stuff the plumbers with food before they are weighed down by the "gifts" and Mario will realize its to late after reading a book called Mega Moles in the Mist. Another group of Monty Moles will attack the Mario Bros. and cause a Game Over, if they go down the dark portion of the Majikoopa's Fortress with a flashlight.